Oral Food Desensitization in Children With IgE-Mediated Cow's Milk Allergy: Immunological Changes Underlying Desensitization
نویسندگان
چکیده
منابع مشابه
Oral Food Desensitization in Children With IgE-Mediated Cow's Milk Allergy: Immunological Changes Underlying Desensitization
PURPOSE This study aimed to evaluate the safety and efficacy to induce clinical desensitization to cow's milk (CM) of an oral immunotherapy (OIT) protocol in a pediatric population with cow's milk allergy (CMA). In addition, the immune responses against β-casein, of peripheral blood mononuclear cells (PBMCs) from CMA patients, before and after the protocol were evaluated and compared to a nonal...
متن کاملOral desensitization in children with cow's milk allergy.
INTRODUCTION Current treatment of food allergies consists of the elimination of the offending food from the diet. Desensitization or tolerance induction can be an alternative for those children who have not achieved tolerance spontaneously. We propose a cow's milk desensitization protocol carried out in an outpatient setting over a 9-10 week period. PATIENTS AND METHOD Eighteen children older...
متن کاملDownregulation of Angiogenesis Factors, VEGF and PDGF, after Rapid IgE Desensitization and Oral Immunotherapy in Children with Food Allergy
BACKGROUND Angiogenesis has a key role in several conditions and is regulated by several factors such as the platelet-derived growth factor (PDGF) or the vascular endothelial growth factor (VEGF). The goal of this study was to investigate the possible role of PDGF and VEGF in a group of patients with severe food allergy. METHODS We design a prospective longitudinal study (n = 30) with patient...
متن کاملThe oral food desensitization in the Italian allergy centres.
BACKGROUND Attempts aimed at inducing food tolerance through oral food desensitization (OFD) for the treatment of IgE-mediated food allergies are increasing. In Italy, a number of allergy centres offer this procedure. OBJECTIVE To collect information on how these centres are organized, how patients are selected, the methods used to administer OFD and how adverse reactions are managed. METHO...
متن کاملRe: Oral desensitization as a useful treatment in 2-year-old children with cow's milk allergy.
BACKGROUND Limited published evidence shows oral desensitization to be a potential intervention option for cow's milk protein (CMPs) allergy. OBJECTIVE The aim of this study was to evaluate the safety and efficacy of oral desensitization in 2-year-old children with cow's milk allergy, as a treatment alternative to elimination diet. METHODS A total of 60 children aged 24-36 months with IgE-m...
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ژورنال
عنوان ژورنال: Allergy, Asthma & Immunology Research
سال: 2017
ISSN: 2092-7355,2092-7363
DOI: 10.4168/aair.2017.9.1.35